Research Articles

2017  |  Vol: 3(3)  |  Issue: 3(May-June)
Neemax Induced Histological Changes in the Liver of Cyprinus carpio

Prerna Pahariya*1, Rajendra Chauhan2, Vipin Vyas3

1Department of Environmental Science and Limnology, Barkatullah University, Bhopal, M.P. India.

2Government Motilal Vigyan Mahavidyalaya, Bhopal, M.P. India.

3Deptartment of Bio Science, Barkatullah University, Bhopal, M.P. India.

Address for Corresponding Author

Prerna Pahariya

Department of Environmental Science and Limnology,

Barkatullah University, Bhopal, M.P. India.



Objective: The aim of this study, was to evaluate the toxicity effect of Neemax on liver of common carp (Cyprinus carpio) as histological biomarkers through acute and chronic exposure with different concentrations. Material and methods:  The toxic effects of Neemax on liver of fish, Cyprinus carpio were studied. Fishes were starved for first 24 h and then fed with rice bran mixed mustard oilcake in the ratio of 2:1 during acclimatization. There are 6-10 specimens exposed to the sub lethal dose for the 15, 30, 45 days with a control group simultaneously. After a particular time, fishes were sacrificed and liver tissue was muscle dissected for histology. Results and conclusion: The result showed remarkable effect of Neemax toxicity as compared to the control group. Liver appeared with multiple markers such as hepatocytes degeneration, increased sinusoids and marked degeneration with necrosis and none of these morphological changes were found in control fish.

Keywords: Toxicity, Cyprinus carpio, Histological markers, Neemax

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