Diksha Saini, Monika Gupta*
Department of Pharmaceutical Chemistry, A.S.B.A.S.J.S.M. College of Pharmacy, Bela, 140111(Punjab), India
Dr. Monika Gupta
Department of Pharmaceutical Chemistry, A.S.B.A.S.J.S.M. College of Pharmacy, Bela, 140111 (Punjab), India
Hydrazone derivatives of carbonyl compounds considered to be biologically important class of compounds. Literature studies revealed that hydrazones and various substituted hydrazones are associated with a broad spectrum of biological activities such as antioxidant, antibacterial, antiviral, analgesic, antiplatelet, antimicrobial, and anticancer. The present paper is focused on the overview of the literature ﬁndings of the last four years (2014–2017) covering the research on anticancer activity of hydrazone derivatives.
Keywords: Hydrazones, cytotoxicity, Anti proliferative, tubulin polymerization