Research Articles

2019  |  Vol: 5(4)  |  Issue: 4 (July- August)  |  https://doi.org/10.31024/ajpp.2019.5.4.21
Cytotoxicity activity of Erythrina indica flowers and separation of essential oil

S. Vijaya Bharathi*, Gargi Srivastava

Department of Biotechnology

FSH, SRMIST, Kattankulathur, Tamilnadu- 603203, India

*Address for Corresponding Author

S. Vijaya Bharathi

Department of Biotechnology

FSH, SRMIST, Kattankulathur, Tamilnadu- 603203, India

Abstract

Objective: To study the anticancer potential and separation of essential oil from flowers of Erythina indica. Material and methods: Antibacterial efficiency was checked by well diffusion method. In to the prepared Muller Hinton agar plates, test cultures were swabbed, incubated for 24 hours. Then well was made and added different concentrations of extract. Cytotoxicity test was done by adding various concentration of extract to the cell lines, incubated and finally MTT solution was added. Formazan formation was measured at 550nm. Cell morphology was checked by microscopy analysis and steam distillation was carried out to separate essential oil. Results and conclusion: Among the 5 test organism analysed, extract showed maximum zone of inhibition for S. aureus. It was identified that the flower ethanol extract was effective against both the cell lines with the cytotoxicity % of 71.26 towards HepG2 and against MG-63 showed 67.11. Hydrosol and the essential oil have to check for its chemical composition, pharmaceutical applications.

Keywords: Erythrina indica, antibacterial, HepG2, hydrosol

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