Case Reports

2018  |  Vol: 4(1)  |  Issue: 1(January-February)  |  https://doi.org/10.31024/ajpp.2018.4.1.15
Olmesartan: An overlooked cause for non-celiac sprue like enteropathy

Avnish Seth1, Varun Gupta*1, Priti Jain2

1Department of Gastroenterolgy and hepatology, Fortis memorial research Institute Gurgaon, India

2Department of Pathology, Fortis Memorial research Institute, Gurgaon, India

*Address for Corresponding Author

Dr. Varun Gupta

Department of Gastroenterolgy and Hepatology, Fortis Memorial Research Institute Gurgaon, India

Abstract

Objective: Chronic diarrhea is a frequently encountered clinical problem and is often challenging to diagnose. During the evaluation of chronic diarrhea, enteropathy is commonly found, but a specific etiology is not achieved. A drug-induced enteropathy is overlooked quite often. Methods: Olmesartan is an angiotensin II receptor blocker (ARB), and is frequently prescribed by physicians in India. We present a case of 51 years female; who was managed for repeated episodes of sever diarrhea requiring repeated hospital admission for dehydration and acute kidney injury. Results and conclusion: On evaluation she was found to have enteropathy for which no cause could be elicited. She remained undiagnosed for months with persisted symptoms until an observation between her symptoms and olmesartan was observed. Her symptoms and enteropathy promptly resolved after discontinuing olmesartan. In this article a short review for the possible differential diagnosis for sprue like enteropathy will also be discussed.

Keywords: Olmesartan, chronic diarrhea, non-celiac enteropathy

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