Review Articles

2018  |  Vol: 4(6)  |  Issue: 6 (November-December)  |  https://doi.org/10.31024/ajpp.2018.4.6.2
Role of freeze drying technology in the development of orally disintegrating films

Ritesh R. Bhirud1, Suvarna A. Katti2*,

1Department of Pharmaceutical Quality Assurance, M.G.V’s Pharmacy College, Panchavati, Nashik-03, Maharashtra, India

2Department of Pharmaceutical Chemistry, M.G.V’s Pharmacy College, Panchavati, Nashik-03, Maharashtra, India

*Address for Corresponding Author

Suvarna A. Katti

Department of Pharmaceutical Quality Assurance, M.G.V’s Pharmacy College, Panchavati, Nashik-03, Maharashtra, India

Abstract

Amongst Oral Drug Delivery System, Orally disintegrating film Technology (ODFT) has gained much attention. The significant advantages of ODFT are it overcomes difficulty in swallowing of oral dosage forms for the administration to pediatric and geriatric population and it is an alternate platform for molecules that undergo first pass metabolism. Thus it shortens onset time, enhances bioavailability and reduces the probability of first pass side effect. The current review describes recent developments in the oral disintegrating films, which includes various techniques for preparation of film and evaluation of oral disintegrating films. This review highlights role and application of freeze drying technology in formulation of orally disintegrating films and evaluation parameters of ODF.

Keywords: Orally disintegrating film, freeze dried film, flash release, thin film strips

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