Research Articles

2019  |  Vol: 5(2)  |  Issue: 2(March-April)  |
Antiepileptic drugs and quality of life in patients with epilepsy: A tertiary care hospital-based study

Rizaldy Taslim Pinzon*, Fransiscus Buwana, Rosa De Lima Renita Sanyasi, Andre Dharmawan Wijono, Jesisca

Faculty of Medicine Duta Wacana Christian University, Yogyakarta, Indonesia

*Address for Corresponding author

Rizaldy Taslim Pinzon

Dr. Wahidin Sudirohusodo 5-25, Yogyakarta, Indonesia, 55224


Background: Epilepsy rates are still high in developing countries, particularly in the case of Indonesia. It becomes big problem since it often leads to the risk of social discrimination/isolation, fear and social stigma. In spite of that, giving a proper treatment to patients with Epilepsy may help them to manage the epilepsy and improve the life quality of the patient. Objective: The present study evaluated patterns of the use of anti- epileptic drugs (AEDs) and their impact on quality of life (QOL) in patients with epilepsy. Materials and Methods: In this cross sectional study, the subjects were epileptic patients ≥ 18 years of age who were diagnosed with epilepsy in Neurological Outpatient Clinic Bethesda Hospital. Demographic, clinical and treatment parameters were recorded. The evaluated outcome was the value of adjusted SF-8 Questionnaire. Results: From 29 patients, 51.72% were males and 58.62% were younger than 60 years. Seizures were predominantly general (89.65%) and partial (10.34%). Patients with immediate therapy were more often found than the delayed therapy (79.31% vs. 20.69%). Patient with delayed therapy have low general health score (40.56 ± 9.07). Twenty six (89.65%) were on monotherapy, two were on two drugs (6.89%) and one patients received more than two drugs (3.44%). Patients with more than one drugs have low general health score (42.70 ± 14.33). Most patients got therapy less than 18 year (96.55% vs. 1.03%). Patient who got therapy more than 18 years have low general health score (32.56). Conclusion: Patients got immadiate therapy, monotherapy anti-epileptic drugs and less than 18 years have a better quality of life.

Keywords: epilepsy, anti-epileptic drugs, quality of life

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