Research Articles

2019  |  Vol: 5(2)  |  Issue: 2(March-April)  |  https://doi.org/10.31024/ajpp.2019.5.2.5
Antiepileptic drugs and quality of life in patients with epilepsy: A tertiary care hospital-based study

Rizaldy Taslim Pinzon*, Fransiscus Buwana, Rosa De Lima Renita Sanyasi, Andre Dharmawan Wijono, Jesisca

Faculty of Medicine Duta Wacana Christian University, Yogyakarta, Indonesia

*Address for Corresponding author

Rizaldy Taslim Pinzon

Dr. Wahidin Sudirohusodo 5-25, Yogyakarta, Indonesia, 55224

Abstract

Background: Epilepsy rates are still high in developing countries, particularly in the case of Indonesia. It becomes big problem since it often leads to the risk of social discrimination/isolation, fear and social stigma. In spite of that, giving a proper treatment to patients with Epilepsy may help them to manage the epilepsy and improve the life quality of the patient. Objective: The present study evaluated patterns of the use of anti- epileptic drugs (AEDs) and their impact on quality of life (QOL) in patients with epilepsy. Materials and Methods: In this cross sectional study, the subjects were epileptic patients ≥ 18 years of age who were diagnosed with epilepsy in Neurological Outpatient Clinic Bethesda Hospital. Demographic, clinical and treatment parameters were recorded. The evaluated outcome was the value of adjusted SF-8 Questionnaire. Results: From 29 patients, 51.72% were males and 58.62% were younger than 60 years. Seizures were predominantly general (89.65%) and partial (10.34%). Patients with immediate therapy were more often found than the delayed therapy (79.31% vs. 20.69%). Patient with delayed therapy have low general health score (40.56 ± 9.07). Twenty six (89.65%) were on monotherapy, two were on two drugs (6.89%) and one patients received more than two drugs (3.44%). Patients with more than one drugs have low general health score (42.70 ± 14.33). Most patients got therapy less than 18 year (96.55% vs. 1.03%). Patient who got therapy more than 18 years have low general health score (32.56). Conclusion: Patients got immadiate therapy, monotherapy anti-epileptic drugs and less than 18 years have a better quality of life.

Keywords: epilepsy, anti-epileptic drugs, quality of life

Manuscript Management System
Submit Article Subscribe Most Popular Articles Join as Reviewer Email Alerts Open Access
Our Another Journal
Another Journal
Call for Paper in Special Issue on

Call for Paper in Special Issue on