Review Articles

2018  |  Vol: 4(2)  |  Issue: 4(March-April)  |  https://doi.org/10.31024/ajpp.2018.4.2.2
Microspheres as suitable drug carrier in Sustained Release Drug Delivery: An overview

Maya Sharma, Suresh Kumar Dev, Manish Kumar, Ajay Kumar Shukla*

Mohanlal Sukhadia University, Udaipur, Rajasthan-313001, India

*Address for Corresponding Author

Ajay Kumar Shukla

Mohanlal Sukhadia University Udaipur-313001, Rajasthan India

Abstract

The word “sustained release” is recognized to have existed in the medical and pharmaceutical literature for many decades. Oral drug delivery is the most preferred route for the various drug molecules among all other routes of drug delivery, because ease of administration which lead to better patient compliance. The goal of any drug delivery system is to supply a therapeutic quantity of drug to the suitable site in the body and then maintain the desired drug concentration. A well designed controlled drug delivery system can overcome some of problems of conventional therapy and enhance therapeutic efficacy of the given drug. There are different approaches in delivering therapeutic material to the goal site in sustained release fashion. One such approach is of the microspheres as carriers for drug. There are various departments of medicine like cancer, pulmonary, cardiology, radiology, gynecology, oncology and diabetes etc, number of drugs are used and they delivered by various types of drug delivery system. Among the sustained release of drugs has gained enormous attention due to its wide range of application and maximum time up to drug release. Moreover the microspheres are of micron size so they can easily fit into various micron size capillary beds. The main purpose of this review is to compile various types of sustained release microspheres, method of preparation, its application and also various parameters to evaluate their efficiency.

Keywords: Microspheres, sustained release, characterization

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