Ajay Kumar Shukla1, Rajesh Shukla2, Vikas Pandey2
1Department of Pharmaceutical Science, Mohanlal Sukhadia University Udaipur Rajasthan
2Guru Ramdas Khalsa Institute of Science and Technology Pharmacy Jabalpur M.P.
Mr. Ajay Kumar Shukla
Mohanlal Sukhadia University, Udaipur Rjasthan, India.
Objective: The goal of this study was to determine the preliminary antibacterial activity of Methanolic extract of Selaginella bryopteris, belonging to family selaginellaceae. Materials and methods: The antibacterial activity of the methanolic extract was done on some standard and wild pathogenic bacterial strains such as Staphylococcus aureus, Staphylococcus epidermidis, Bacillus cereus, Bacillus subtilis, Escherichia coli and Salmonella typhi. The testing was done by the agar cup plate method. Zone of inhibition of extract (50, 100 and 150 mg/ml) was compared with standard Amoxicillin (0.5 and 1 mg/ml) prepared in DMSO. Results and conclusion: The extract shows prospective antibacterial properties comparable with that of standard amoxicillin against the organisms tested. The methanolic extract of Selaginella bryopteris displayed a concentration related antibacterial activity. The results show that the inhibition of the bacterial growth was more pronounced on Escherichia coli as compared to the other tested organisms.
Keywords: Selaginella bryopteris, Antibacterial, E. coli, Zone of inhibition, aqueous infusion, aqueous decoction