Research Articles

2019  |  Vol: 5(5)  |  Issue: 5(September- October)  |  https://doi.org/10.31024/ajpp.2019.5.5.15
Antioxidant and antibacterial activity of Hygrophila spinosa T Anders root extracts

P. Venugopalan*, C.  N. Nimisha

Department of Chemistry,

Sree Neelakanta Government Sanskrit College Pattambi, (Affiliated to the University of Calicut) Kerala- 679306, India

*Corresponding Author

P. Venugopalan

Department of Chemistry

Sree Neelakanta Government Sanskrit College Pattambi

(Affiliated to the University of Calicut)

Kerala- 679306.  India

Abstract

Objective: In recent years, medical plants used in folk medicine represent a suitable approach for the development of new drugs. In this context, herein we report the antioxidant and antibacterial activity of the extracts of the roots of medicinal plant Hygrophila spinosa T Anders Materials and methods: The roots of Hygrophila spinosa were extracted with n-hexane, dichloromethane and ethyl acetate. A few common compounds in the extracts were identified by GC MS analysis. Antioxidant activity of the crude extracts was compared by measuring DPPH radical scavenging activity, super oxide radical scavenging activity and lipid peroxidation inhibitory activity. The antibacterial properties of the extracts were tested against Staphylococcus aureus (ATCC 25923) and Escherichia coli (ATCC 25922) by disc diffusion method. Results: The antioxidant activity of Hygrophila spinosa root extracts were established by different methods. The extracts showed moderate to good antibacterialactivity against both Gram-positive and Gram-negative tested organisms. Conclusions: The studies presented here reveal the antioxidant and antibacterial activity of Hygrophila spinosa root extracts.

KeywordsHygrophila spinosa T Anders, antioxidants, antioxidant activity, DPPH, medicinal plants, antibacterial agents

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