Review Article

2020  |  Vol: 6  |  Issue: 2 (Articles in Press)  |  https://doi.org/10.31024/ajpp.2020.6.2.4
Varuna (Crataeva nurvala Buch. Ham.): A Brief review on Phytochemistry, Pharmacological profile and uses in various ailments

Swati Vashist1, Manjusha Choudhary1*, Shammi Rajpal2, Deepali Siwan2, Vikas Budhwar3

1Institute of Pharmaceutical Sciences, Kurukshetra University, Kurukshetra-136119, India

2Ayucare Pharma, 38, Bhagat Singh Market, Hisar-125001, India

3Department of Pharmaceutical Sciences, Maharishi Dyanand University, Rohtak-124001, India

*Address for Corresponding Author

Manjusha Choudhary

Institute of Pharmaceutical Sciences, Kurukshetra University, Kurukshetra-136119, India


Abstract

Crataeva nurvala Buch Ham (Capparidaeae), commonly known as Varuna, is an evergreen tree indigenous to India. It grows widely in all parts of world. Traditionally, it is as anti-periodic for waste elimination, breathing problems, metabolic disorders, joint lubrication, skin moisture, wound healing etc. Barkis cytotoxic, useful in urinary disorders, kidney, bladder stones, fever, vomiting, gastric irritation, contraceptive and oxytocic; bark-juice is given post-pregnancy. Leaves are rubefacient (external application), anti-rheumatic; internally used as febrifuge and tonic. Phytoconstituents present in the plant include lupeol, lupeol-acetate, spinasterol acetate, taraxasterol, 3-epilupeol, cadabacine, cadabacine acetate, catechin, epicatechin-5-glucoside, epifzelechin and glucocapparin, pentadecane, octanamide, 12-tricosanone and friedelin etc. Reported activities included antidiabetic, antibacterial, anthelmintic, anti-nociceptive, contraceptive, antiurolithiatic, anti-fertility, anti-inflammatory, antidiarrhoeal, wound-healing, analgesic, cardioprotective and antimalarial properties of C. nurvala. This review includes detailed exploration of the botany, phtyochemistry and pharmacologial aspects of C. nurvala. This is an attempt to provide a direction of further research.

Keywords: Crataeva nurvala, pharmacology, phytochemistry, toxicity

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