Research Articles

2019  |  Vol: 5(5)  |  Issue: 5(September- October)  |  https://doi.org/10.31024/ajpp.2019.5.5.3
Free radical scavenging activity of methanolic extract of marine red algae Actinotrichia fragilis

Baskaran Krishnan*, Rathi M. A., Nirmaladevi N.

Department of Biochemistry, Sree Narayana Guru College, Coimbatore, Tamilnadu, India

*Correspondence  Author:

Dr.  K. Baskaran, M.Sc., M.Phil., Ph.D.  

Assistant Professor

Department  of  Biochemistry, Sree Narayana Guru College, Coimbatore-641105 Tamilnadu, India

Abstract        

Objective: Antioxidants in seaweeds have attracted increasing interest for its role in protecting human health. The present study was designed to assess the antioxidant and reactive oxygen species (ROS) scavenging activities of 70% methanol extract of the red algae Actinotrichia fragilis.  Material and Methods: The evaluation of antioxidant properties was determined by 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2’-azinobis 3ethylbenzthiazoline-6-sulphonic acid (ABTS), ferric reducing antioxidant power (FRAP), nitric oxide scavenging assay (NO),  reducing power,  hydroxyl, superoxide radical scavenging (SOD), hydrogen peroxide radical assay, the metal chelating activity as well as phosphomolypdenum assay.  Results: Among the tested red algae, the maximum antioxidant activity was recorded in the methanol extract of Actinotrichia fragilis. Whereas methanol crude extract of red algae and diatom showed good antioxidant potential. Conclusion: This study suggests that methanol crude extracts contain different potential antioxidant compounds capable to scavenge different types of free radicals.

Keywords: Actinotrichia fragilis, Free radical scavenging, Antioxidant activity

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