Research Articles

2019  |  Vol: 5(6)  |  Issue: 6 (November-December)  |  https://doi.org/10.31024/ajpp.2019.5.6.3
Antioxidant activity of ethanolic and aqueous extracts of Alternanthera pungens Kunth

Pramod Mourya* Neeraj K. Sharma, M. K. Gupta

Oriental College of Pharmacy and Research, Oriental University, Indore M.P. India

*Address for Corresponding Author

Pramod Mourya

Oriental College of Pharmacy and Research, Oriental University, Indore M.P. India

Abstract

Objective: The objective of present work to evaluates in-vitro antioxidant activities of the ethanolic and aqueous extracts of Alternanthera pungens Kunth. Material and methods: The antioxidant activity and phenolic contents of the whole plant were determined by the DPPH and ABTS scavenging method. The DPPH and ABTS scavenging activity were compared with standard Ascorbic acid and BHT. Results: The DPPH assay revealed that at a conc. of 100 mg/ml, the scavenging activity of ethanolic extract reached 61.92 % while at the same conc., that the aqueous extract was 30.90 %. The effect of antioxidants on DPPH is due to their hydrogen donating ability. Though the DPPH radical scavenging abilities of the extracts were less than those of ascorbic (77.27 %) and BHT (96.12 %) at 100 mg/ml, the ethanolic extracts have the proton- donating ability and could serve as free radical inhibitors or scavengers. Conclusion: The ethanolic extract demonstrates potent antioxidant activity in different concentration. The total phenolic content in plant may play a major role as an antioxidant. The result of this study shows that the ethanolic extract can be used as easily accessible source of natural antioxidants and as possible food supplement.

Keywords: Antioxidant, Alternanthera pungens KunthDPPH and ABTS scavenging method, ascorbic acid

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