Pavithra P.1*, Raga Priya S.1, Pritha K.1, Priyanka S.1, Rema A.1, Pavazhaviji P.2, Jayaraman Rajangam1
1Department of Pharmacology, Shri Venkateshwara College of Pharmacy, Ariyur, Puducherry-605102
2Department of Pharmaceutics, School of Pharmaceutical Sciences, Vels Institute of Sciences, Technology and Advanced Studies, Pallavaram, Chennai, Tamil Nadu-600043
*Address for Corresponding Author
Pavithra P.
Department of Pharmacology, Shri Venkateshwara College of Pharmacy, Ariyur, Puducherry-605102
Abstract
The host immune system possesses an intrinsic ability to target and kill cancer cells in a specific and adaptable manner that can be further enhanced by cancer immunotherapy, which aims to train the immune system to boost the antitumor immune response. This review consists of various types of nano carriers used for cancer therapy. Several different categories of cancer immunotherapy have emerged as new standard cancer therapies in the clinic, including cancer vaccines, immune checkpoint inhibitors, adoptive T cell therapy, and oncolytic virus therapy. Despite the remarkable survival benefit for a subset of patients, the low response rate and immunotoxicity remain the major challenges for current cancer immunotherapy. Over the last few decades, nanomedicine has been intensively investigated with great enthusiasm, leading to marked advancements in nanoparticle platforms and nanoengineering technology.
Keywords: Nanomedicine, immunotherapy, nanoengineering, vaccines, cancer
