Research Articles

2022  |  Vol: 8(3)  |  Issue: 3 (May- June)  |
Evaluation of Anogeissus latifolia Roxb on complete freund’s adjuvant induced arthritis in albino rats

P. Mumthaj*, Natarajan P.

Sankaralingam Bhuvaneshwari College of Pharmacy, Sivakasi, Tamil Nadu, India

*Address for Corresponding author

P. Mumthaj

Department of Pharmacology

Sankaralingam Bhuvaneshwari College of Pharmacy, Sivakasi-626130 Tamil Nadu, India



Objective: The aim of the present research work is to evaluate the anti arthritis activity of Anogeissus latifolia roxb in complete freund’s adjuvant (CFA) induced rats. Material and methods: The ethanolic extract of   Anogeissus latifolia Roxb (EEAL) was administered by the oral in the dose of 200 and 400mg/kg for a period of 21 days respectively. The biochemical, haemotological parameters and histopathology of the joint tissue were performed. The EEAL attenuated the arthritis factors induced by CFA. Results and conclusion: The research  investigation of both extracts was showed better protection against arthritis. In this study both extracts, at the 400mg/kg p.o. dose have more potent effect than the 200mg/kg p.o.. The present study was concluded that EEAL of both concentrations (200 and 400mg/kg p.o.) provides a significant effect in dose dependent manner.

Keywords: Complete freund’s adjuvant, arthritis, Sub plantar, Anogeissus latifolia

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