Narendra Pentu*, Peddapaidi Rishitha, Gudala Nikhil, T. Rama Rao
CMR college of Pharmacy, Kandlakoya (V), Medchal, Telangana-501401 India
*Address for Corresponding author
Narendra Pentu
Assistant Professor
CMR college of Pharmacy, Kandlakoya(V), Medchal, Telangana-501401
ORCID ID: 0000-0001-6255-9254
Abstract
Psoriasis is a common inflammatory skin disorder, caused by the various environmental, genetical factors. Plaques formation, itching, redness of skin are the common symptoms in the long run. there are several types of diseases based on the types of puples present on the skin like plaque, postular, guttate, inverse and erythrodermic. Around 125 million population throughout the world suffering with this disease with several comorbidities like psoriatic arthritis, cardiovascular diseases. Treatment available based on severity of the disease. topical, oral, systemic and phototherapy are available and the current treatment is boosted for the usage of biologics manufactured based on the mab’s to regulate psoriasis some extent. But, these therapies cause serious life threatening side effects like hypersensitivity reactions, upper urinary tract infections and several neurological diseases. The present study was aimed to usage of plant products in the treatment of psoriasis like Flavanoids. These natural compounds are already proved for their anti oxidant, anti inflammatory and anti proliferative properties, which are very much useful in the psoriasis treatment. Flavonoids are secondary metabolites derived from the plants and used to improve the defense mechanism in plants. Psoriasis is a life time disease with no permanent treatment. Usage of natural compounds may improve the quality of life and reduce the side effects caused by the chemical compounds.
Keywords: Phototheraphy, psoriasis, comorbidities, flavonoids, nutraceuticals, inflammatory
