Bhavani Dhomakonda*, Korra Eshwari, Narra Amulya, Purumala Sairam Reddy, Tadikonda Rama Rao
Department of Pharm D, CMR College of Pharmacy, Hyderabad, Telangana, India
*Address for Correspondence Author:
Dhomakonda Bhavani,
Department of Pharm D, CMR College of Pharmacy, Hyderabad, Telangana, India
Abstract
Monkeypox is a zoonotic viral infection caused by the monkeypox virus. It belongs to the ortho poxvirus genus in the poxviridae family and can infect humans as well as other animals. It is a DNA virus with an enclosed double standard. Since the virus was first identified in macaque monkeys in 1958, it has been referred to as "monkeypox." The initial signs and symptoms are a fever, headache, and muscle aches. When instances of monkeypox began to rise in the 1970s and the smallpox vaccine program was terminated, the world took note. Recently, there has been a notable outbreak of the monkeypox virus in central Africa, and the infection's threat to public health is constantly growing. As of right now, the monkeypox virus has been classified into two genetic clades: the clades of western and central Africa. The most common clinical manifestation seen in people with monkeypox is mucocutaneous presentation. Despite the lack of a proven, safe treatment, antivirals, which were first developed for use in smallpox patients-are being used to treat monkeypox. In severe cases, medication like Tecovirimat may be administered. We have discussed a number of subjects in this article, including outbreaks, immunizations, therapies, transmission, and worldwide prevalence, in an effort to improve understanding of monkeypox and to set the stage for future research.
Keywords: Monkeypox, orthopox, zoonotic, tecovirimat, immunization, vaccination, smallpox, iymphadenopathy, encephalitis
