Sristi Singh1*, Yogendra Mavai1
1Department of Pharmacology, Shriram College of Pharmacy, Banmore, Gwalior (M.P.) India
*Correspondence Address
Sristi Singh
Department of Pharmacology, Shriram College of Pharmacy, Banmore, Gwalior (M.P.), India
Abstract
Objective: To investigate the role of cow urine, A2 milk and wheatgrass juice on alloxan induced diabetes in male Wistar rats and to compare it. Diabetes mellitus (DM) is a complex chronic illness associated with a state of high blood glucose level, or hyperglycemia, occurring from deficiencies in insulin secretion, action, or both. There are various herbal treatment available for treating diabetes like wheatgrass (containing chrophyll), cow urine, A2 milk (milk obtained from Indian breed of cows). Materials and methods: Forty two animals were randomized into seven groups. Group 1-normal control; Group 2- diabetic control; Group 3 – cow urine(1ml/kg, twice a day); Group 4- A2 milk (as supplementary diet); Group 5- wheatgrass juice(30ml/kg, twice a day); Group 6- combination of all three; group 7- std.(glibenclamide,0.5 ml/kd, once a day). All the animals were sacrificed on 21st day and blood, serum and organs (liver, heart, and kidney) were collected for biochemical and histopathological study. Results: It was seen that wheatgrass juice and combination treatment showed better antidiabetic efficacy as compared to cow urine and A2 milk. Conclusion: Our results have showed that herbal treatment/ drugs have the potency to treat diabetes and are also non-toxic.
Keywords: Insulin, hyperglycemia, Glibenclamide, cow urine, A2 milk, wheatgrass juice
