Sailesh Narayan*
Department of Pharmacology, Radharaman College of Pharmacy, Bhopal, Madhya Pradesh, India
*Address for Corresponding Author
Prof. Sailesh Narayan
Department of Pharmacology, Radharaman College of Pharmacy, Bhopal, Madhya Pradesh, India
Abstract
Objective: The objective of the present work is to study for an in-vitro anti-oxidant activity of petroleum ether, ethyl acetate and methanolic extracts of leaves of Salvia splendens. Material and methods: The extracts were studied using 1,1-diphenyl-2-picryl hydrazyl, hydrogen peroxide (H2O2), total phenolic content (TPC) and total flavonoid content (TFC). The TPC and TFC were estimated taking gallic acid and rutin calibration curve respectably. Results: All the extracts possess in-vitro anti-oxidant activity. However, the order of possessing activity was methanolic > ethyl acetate > petroleum ether extracts of S. splendens leaves. The TPC and TFC were highest in methanolic extract. Conclusion: It can be concluded that the extract of the leaves of S. splendens, possess anti-oxidant activity. The methanolic extract of the leaves of S. splendens, possess highest anti-oxidant activity in-vitro.
Keywords: Salvia splendens, anti-oxidant, 1,1-diphenyl-2-picryl hydrazyl, phenolic content, flavonoid content