Research Articles

2019  |  Vol: 5(3)  |  Issue: 3 (May- June)  |  https://doi.org/10.31024/ajpp.2019.5.3.22

Identification, isolation and elucidation of compounds from fraction of methyl hydroxyl chalcone polymer from aqueous extract of Cinnamomum Zeylaynicum

T. Sivapriya¹*, Sheila John²

¹Asst Professor, Department of Clinical Nutrition and Dietetics, SDNB Vaishnav College for Women, Chrompet, Chennai, TamilNadu, India

²Head and Associate Professor, Department of Home Science, Women’s Christian College, Chennai, India

*Address for Corresponding Author

Dr. T. Sivapriya

Department of Clinical Nutrition and Dietetics, SDNB Vaishnav College for Women, Chrompet, Chennai, Tamil Nadu, India

Abstract

Objective: Cinnamon has been touted as an alternative medicine for type 2 diabetes in recent times. There has been multitude of discrepancies about the bioactive compound responsible for insulin sensitising action. The objective of the study is to purify, identify, isolate and elucidate the molecular structure of bio active compounds present in enriched fraction of methyl hydroxyl chalcone polymer (MHCP) in Cinnamomum zelaynicum (CZ). Materials and methods: Phytochemical screening was carried out to detect the presence of phytochemicals present. Aqueous extract of CZ was subjected to   purification and isolation of the enriched fraction of (MHCP). Then the chemical structure of the enriched fraction of (MHCP) was elucidated using spectroscopic techniques like infrared spectroscopy, nuclear magnetic resonance and mass spectroscopy. Results and Conclusion: MHCP enriched fraction was subjected FT infrared analysis, nuclear magnetic resonance spectroscopy and mass spectrometry. The bioactive compounds identified were Ellagic acid 3-O-pentoside, Afzelechin 3-O-glucopyranoside, gallocatechin 3-O-pentoside.

Keywords: Cinnamon, phytochemical, type 2 Diabetes, insulin, sensitivity